Protein Vpx

Intermolecular

Cysteine 1113 of DDB1- and CUL4-associated factor 1 and cysteine 73

A redox-regulated disulphide may form between cysteine 1113 of DDB1- and CUL4-associated factor 1 and cysteine 73 of Protein Vpx.

Details

Redox score ?

PDB code

4cc9

Structure name

crystal structure of human samhd1 (amino acid residues 582-626) bound to vpx isolated from sooty mangabey and human dcaf1 (amino acid residues 1058-1396)

Structure deposition date

2013-10-19

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide A name

DDB1- and CUL4-associated factor 1

Peptide B name

Protein Vpx

Peptide A accession

Q9Y4B6

Peptide B accession

P19508

Peptide A residue number

1113

Peptide B residue number

Ligandability

Cysteine 1113 of DDB1- and CUL4-associated factor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.